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differential oncology causes treatment algorithm classification dermatology signs sle symptoms workup disease erythematosus hemolytic systemic hemolysis leukemia monoclonal neurology aplastic
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
temporalis (giant-cell ... - systemic lupus ... #Vessels #Diagnosis ... #Rheumatology # ... Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... - Sickle cell anemia ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... • ANCA Vasculitis ... Autoantibodies #Rheumatology ... #diagnosis #associations
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
recurrent fevers, vasculitis ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic ... (12%) • giant cell ... Autoinflammatory #Somatic #rheumatology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Pelger-Huet, Macrocytic anemia ... or λ), Smudge Cells ... Blood #Disorders #hematology ... #Differential #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... cytopenias (usually anemia ... Allogeneic stem cell ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... usually IgG) (e.g. lupus ... , CLL, lymphoma, ... #hematology #anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... , Vasculitides, ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
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