105 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... Hyperviscosity Syndrome ... neutrophil count < 500 cells ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... = funny-shaped cells ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
melanocyte that activate ... #Pathophysiology ... #Oncology #Melanoma
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
harmful -> Th Cells ... activate macrophages ... , mast cells or ... Stevens-Johnson Syndrome ... Allergy #Immunology #pathophysiology
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Irritable Bowel Syndrome ... (IBS) - Pathophysiology ... Diagnosis and Management ... #Pathophysiology ... #Diagnosis #Management
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Transcellular Shift Into Cells ... imports K+ into cells ... - Refeeding Syndrome ... potassium #low #pathophysiology
Tetralogy of Fallot Summary
 • Anatomy
 • Incidence
 • Pathophysiology
 • Presentation
 • Common Variants
 •
• Incidence • Pathophysiology ... Associated Genetic Syndromes ... palliation • Post-Op Management ... Fallot #diagnosis #management
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Irritable Bowel Syndrome ... (IBS) - Management ... Secretagogues → activate ... intestinal epithelial cells ... Irritable #Bowel #Syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... Aplastic #Anemia #oncology ... hematology #diagnosis #management
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Tubule Epithelial Cells ... limb Gitelman syndrome ... tubule Liddle syndrome ... Pseudohypoaldosteronism - Decreased activity ... (V2) receptor activity