16 results
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sensitive) • AKI ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... hematuria, mild ... proteinuria, granular casts
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria - Differential ... urine • 1ml blood ... : - RBC casts ... #Differential # ... #urology #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... ) - Differential ... Epithelial cell casts ... polyangiitis /microscopic ... #Nephrology #Differential
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Algorithm Red blood ... cells on urine ... microscopy. ... RBCs and/or RBC casts
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
cell casts on UA ... renal tubular cell casts ... or pigmented casts ... treating underlying cause ... Kidney #Injury #AKI
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... are seen in acute ... 34t5DgJ #Urinary #Casts
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... dipstick, urine microscopy ... osmolarity If cause ... #Diagnosis #nephrology ... #causes
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Microscopic exam ... • Red blood cells ... • Urinary casts ... (AKI) FE Na < ... leucocyte-esterase #urine #UNa #casts
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... of Peripheral blood ... smear - Shows schistocytes ... proteinuria and hematuria ... (without casts)
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age • 22 and 45 cases ... Peripheral Smear ... count with differential ... smear • Bone marrow ... Syndromes #diagnosis #hematology