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diagnosis algorithm management oncology classification disorders thrombocytosis hemolytic rheumatology secondary workup atlas chronic clinical cll elevatedmcv generalized lymphocytic macrocytosis mds
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Chronic Myelogenous Leukemia ... effect following treatment ... Iron deficiency anemia ... #Hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... /blood loss (Fe ... Chronic Myeloid Leukemia ... #Diagnosis #causes ... #Platelets #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Sickled red cells ... #Peripheral #Blood ... Smear #Analysis #hematology ... #microscopy #interpretation
Dysmorphic Red Blood Cells on Electron Microscopy This eyeSCANdy image shows dysmorphic red blood cells from the
Dysmorphic Red Blood ... Microscopy This ... dysmorphic red blood ... urine of a patient ... clinical #pathology #hematology
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 Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... hepatomegaly • Labs: anemia ... predominant immature cells ... Diagnosis #Algorithm #hematology ... #WBC #Leukemoid
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Neutrophils - Differential ... Chronic myelogenous leukemia ... pancytopenia, blast cells ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphadenopathy - Differential ... Reed-Sternberg Cells ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... #Differential # ... Diagnosis #Algorithm #Causes ... #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... count with differential ... Syndromes #diagnosis #hematology
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