60 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Sickled red cells ... disease Bite cells ... #Peripheral #Blood ... Analysis #hematology #microscopy
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
• stored red blood ... cells - Hb variant ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Differential #Causes
Diagnostic Criteria for Scleroderma Renal Crisis 

1. New onset blood pressure >150/85 mm Hg OR increase
New onset blood ... Microangiopathic hemolytic anemia ... examination - Microscopic ... cells on urine ... microscopy -
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... by blood cells ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Plasmodium Falciparum Blood ... P. falciparum causes ... human malaria cases ... peripheral #clinical #microscopy ... #microbiology #
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... • Peripheral blood ... History • Bite cells ... Deficiency • Sickle cells ... Diagnosis #Algorithm #causes
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... polychromatophilic cells ... Pathology #Smear #Microscopy
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... is rare (< 10% cases ... ), cough (30% cases ... immature forms) • Anemia ... Infection #diagnosis #microbiology
Salmonella Aspiration on Microscopy

66 y/o male with history of coronary artery disease presents with abdominal pain.
Aspiration on Microscopy ... CT abd/pelvis shows ... Is a major cause ... Salmonella #Aspiration #Microscopy ... clinical #pathology #microbiology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... • Pernicious Anemia ... Macrocytosis, Target Cells ... Diagnosis #Algorithm #Causes