22 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... = funny-shaped cells ... cytopenias (usually anemia ... transformation to acute ... #treatment #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... treatment (examples ... #Syndromes #diagnosis ... #hematology #oncology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Liver diseases, Myelodysplastic ... syndrome, Increased ... Malignant tumors, Acute ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... , Target Cells, ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... kidney disease, Acute ... Hypothyroidism, Myelodysplastic ... syndrome - Dr ... #causes #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... #Causes #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... Normal RBCs • Acute ... #Algorithm #Causes ... #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... Disorders - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... or λ), Smudge Cells ... #Algorithm
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• Hypocellular myelodysplastic ... syndrome (MDS) ... Treatment: ... #oncology #hematology ... #diagnosis #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology