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differential hematology disorders management neurology syndrome aids associated blood classification dementia differentiation fever hand lymphomas lymphoproliferative myelitis neurocognitive nonhodgkin oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... Acute • Myloid ... (AML) - CD13, CD33 ... or λ), Smudge Cells ... Amy Chung, MD, MSc
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
Disorder (HAND) ... dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... psychomotor slowing, marked
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... Release from blast cells ... : >3 symptoms, or ... • Steroids: IV
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Algorithm Hodgkin ... pattern of spread, B symptoms ... Treated Like Acute ... Amy Chung, MD, MSc ... Classification #pathophysiology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... Bilateral signs and/or symptoms ... Pleocytosis > 100 cells ... simplex virus, HIV
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis EPIDEMIOLOGY: PFAPA is the most common syndrome entailing
fever (FMF) PATHOPHYSIOLOGY ... Inflammatory markers ... The diagnosis of ... ), - Muckle–Wells ... contributor to this disorder
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