46 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Management of Sickle Cell ... Management #Diagnosis ... #Management #Hematology ... #SickleCell #Complications ... #Ddxof
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... ) CLL Symptoms: ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Algorithm Pathophysiology ... , vital sign instability ... #Dermatology #Rash ... #Differential #Ddxof
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
cells -> Mutagenic ... / Symptoms / Complications ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... • Lymphoid (CLL ... or λ), Smudge Cells ... Amy Chung, MD, MSc ... Blood #Disorders #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Diagnosis: • ... kinase (BTK) Complications ... workup #oncology #hematology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Algorithm. ... Pathophysiology: ... Dermatology #Rash ... #Differential #Ddxof
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... CRP Neuronal cell ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms ... #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms