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hematology management oncology differential aids ammonia associated chronic classification cll dementia differentiation disorders fever hand hemeonc hemophagocytic hiv hlh hyperammonemia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... #APML #diagnosis
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... CNS ○ Infected cells ... • Depressive symptoms ... Diagnosis: MRI ... The clinical syndrome
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... Algorithm Hodgkin ... pattern of spread, B symptoms ... Classification #pathophysiology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
Inherited Urea Cycle Disorders ... rare): - Reye syndrome ... (Peds) - Primary ... deficiency #Ammonia #Pathophysiology ... #Differential #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... Neutropenia • Platelet Disorders ... progression to AML ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... phenomenon CLL Diagnosis ... lymphoproliferative disorders ... • Richter’s Syndrome ... Transform to DLBCL, PML
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
which is a rare disorder ... cell lymphoma Pathophysiology ... and the systemic symptoms ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... patients with the HLH syndrome ... Common Signs and Symptoms ... Pathophysiology ... malignancy, autoimmune disorder
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis EPIDEMIOLOGY: PFAPA is the most common syndrome entailing
fever (FMF) PATHOPHYSIOLOGY ... The diagnosis of ... ), - Muckle–Wells ... contributor to this disorder ... #Diagnosis
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