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hematology syndrome oncology differential neurology lupus signs leukemia summary algorithm cardiology chronic classification cll comparison disorders druginduced erythematosus hemeonc infectiousdiseases
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology ... #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Positive in 60-80% of cases ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... • Treatment: ... comparison #table #rheumatology ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis of tumor cells ... Syndrome #TLS #diagnosis ... #management #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Autoimmune diseases: SLE ... Treatment: • ... #management #treatment ... #summary #rheumatology
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... functional ID) Treatment ... improvement in symptoms ... #management #cardiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... pattern of spread, B symptoms ... Responsive to Treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
and Management ... Treatment: • Global ... Rifaximin- up to 3 courses ... intestinal epithelial cells ... #treatment
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