26 results
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... of disease and complications ... the sickle red cells ... SickleCell #Disease #Pathophysiology ... #Complications
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
maturation of immune cells ... • Alveolar Cells ... #FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
stimulates granulosa cells ... androgens from theca cells ... #OvarianCycle #pathophysiology ... #menstruation #endocrinology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Pathogenesis and Complications ... turnover and lysis of cells ... WBCs, and skin cells ... Hyperuricemia #Pathophysiology ... #Complications
Amiodarone Thyroid Complications
Amiodarone: 
 - iodine-rich, similar structure to T4, with half life up to 100d
Amiodarone Thyroid Complications ... thyroid follicular cells ... Amiodarone #Thyroid #Complications ... #endocrinology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... RheumaticFever #pathophysiology ... signs #symptoms #complications
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
diffusion of K+ out of cells ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Signs / Symptoms / Complications ... Retinoblastoma #pathophysiology
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Otitis Media: Complications ... to mastoid air cells ... Signs/Symptoms/Complications ... • Intracranial complications ... #pathophysiology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... inward rotation of pelvis ... MSK #diagnosis #complications ... #pathophysiology