13 results
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Differential Diagnosis Algorithm ... Transcellular Shift Into Cells ... imports K+ into cells ... causes #potassium #low ... #pathophysiology
How dendritic cells (DCs) orchestrate adaptive immunity
1- Sensing of microbial and damage signals by DCs
2- Phenotypic
How dendritic cells ... pathways 4- T cell ... adaptive #immunity #immunology ... #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... ~90% • Low Grade ... Classification #pathophysiology
Approach to Hypomagnesemia 

Fractional excretion of magnesium = (urine magnesium x serum creatinine)/ [0.7 (serum magnesium
magnesium into cells ... Hypomagnesemia #algorithm ... diagnosis #causes #nephrology ... #magnesium #low
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... Physiology: CO2: • Low ... water leaves brain cells ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... , Elevated Cr, Low ... TLS #diagnosis #management
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... invades mononuclear cells ... CNS ○ Infected cells ... ARVs can have low ... untreated HIV and with low
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... are the immune cells ... between nerve cells ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Prolonged PT/PTT • Low ... protein C and S Pathophysiology ... Schistocytes, helmet cells ... causes #treatment #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Diagnosis and Management ... Redistribution: Acidosis, Cell ... acidosis) • Low ... Drives K+ into cells ... Treatment #potassium #nephrology