98 results
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Aplastic Anemia ... Definition • Pathophysiology ... #Aplastic #Anemia ... #diagnosis #oncology
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic Anemia ... #Aplastic #Anemia ... #Causes #Pathophysiology ... #Pathology #Treatment ... #Management #Differential
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
stored red blood cells ... • chronic anæmia ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
transfusion • Target cells ... Hemoglobinopathies • Teardrop cells ... • Sickle cells ... alcoholism • Burr cells ... key #diagnosis #differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... , Target Cells ... #Normocytic #Anemia ... #Differential #
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... - Differential ... History • Bite cells ... Deficiency • Sickle cells ... #Differential #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... number of CD34+ cells ... Treatment: ... #oncology #hematology
Dyspnea - Considerations with Malignancy
Directly Malignancy Related:
 - Lymphangitic spread to lung
 - Malignant pleural effusion
metastases Treatment ... - Cytopenias (anemia ... dyspnea #algorithm #differential ... #diagnosis #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... - Differential ... HEMATOLOGIC ONCOLOGIC ... neutrophil count < 500 cells ... #differential #