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diagnosis signs symptoms management classification antiarrhythmics cardiology classes diabetes differential lupus orthopedics sle syndrome caudaequina criticalcare crystalloids diabeticfoot diabeticketoacidosis disruptors
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology
Drug-Induced Edema Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... release from mast cells ... Edema #Medication #Causes ... #Differential #Pharmacology ... #Pathophysiology
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Pathogenesis and Complications ... WBCs, and skin cells ... Release of purine bases ... Hyperuricemia #Pathophysiology ... #Complications
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... Signs / Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... inward rotation of pelvis ... #Orthopedics #MSK ... #diagnosis #complications ... #pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
diffusion of K+ out of cells ... may cause serum ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... DiabeticKetoacidosis #DKA #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... hair follicles -> causes ... removal of these cells ... Manifestations #pathophysiology ... signs #symptoms #complications
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
countries (11-24 cases ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... symptoms are not caused ... anterior/posterior MSK
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... increases out of cells ... Antiarrhythmics #Pharmacology ... Classification #Classes ... #pathophysiology
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
accumulates in cells ... Glycosylation - AGE cause ... #DiabeticFoot #pathophysiology ... #complications
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