Lellis treatment hematology diagnosis workup disease anemia classification systemic acute

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Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

- Differential Diagnosis ... for workup, including ... , deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease

Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
• Artifact (redo CBC)
Autonomous:
• Essential thrombocytosis
• Polycythemia

- Differential Diagnosis ... Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia

Red Blood Cell (RBC) Morphology Atlas
• Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning

, Liver diseases ... Malignant tumors, Acute ... , Liver diseases ... Morphology #Atlas #key #diagnosis ... #differential #hematology

Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
• Acute Bleed - Normocytic / Normochromic

- Differential Diagnosis ... Blood Loss • Acute ... Disease • Marrow ... #Classification ... Algorithm #Causes #Hematology

Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
• Fever, acute onset RUQ pain,

of Sickle Cell Disease ... Supportive with treatment ... hepatomegaly and anemia ... Hepatobiliary #hepatology ... #differential #diagnosis

Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations

Clinical Classification ... Chronic hemolytic anemia ... Systolic dysfunction ... multifactorial mechanisms Hematologic ... #Diagnosis #Differential

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle cells ... #Algorithm #workup ... #hematology #testing

Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells

= funny-shaped cells ... cytopenias (usually anemia ... transformation to acute ... #Management #treatment ... #hematology #oncology

Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells

- Differential Diagnosis ... with lymphatic system ... Treated Like Acute ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology

IgG4-Related Disease
Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
•

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