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diagnosis differential management classification leukemia cancer chronic cll injury lymphocytic tls workup aki apml behcet causes cell dermatology differentiation diffuse
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
tubulopathy • Monoclonal ... change disease • Hematologic ... malignancies Treatment ... lysis syndrome ... #AKI #Cancer #Oncology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... An acute, life-threatening ... & Acute leukemia ... #Lysis #Syndrome ... #TLS #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Fatigue • Acute ... Lymphocytes) - Monoclonal ... Reed-Sternberg Cells ... #Causes #Hematology ... #Oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... - ACS, AKI, acute ... Lysis Syndrome: ... of tumor cells ... #Lysis #Syndrome
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... predominant (LP) tumour ... Responsive to Treatment ... Treated Like Acute ... pathophysiology #Hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... neutrophil count < 500 cells ... EMERGENCIES: Tumor ... Lysis Syndrome: ... Hyperuricemia • Acute
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... Kawasaki, Nephrotic syndrome ... Differential #Diagnosis #Algorithm
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transformation to acute ... only curative treatment ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Classification: • The tumor ... predominant HL - The tumor ... Treatment • Early ... classification #hematology ... #oncology #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... Fibrinolysis & DIC • Tumor ... lysis syndrome: ... #Leukemia #Hematology ... #Oncology #Diagnosis
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