49 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Fatigue • Acute ... Lymphocytes) - Monoclonal ... Reed-Sternberg Cells ... #Hematology #Oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... tubulopathy • Monoclonal ... change disease • Hematologic ... malignancies Treatment ... #AKI #Cancer #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... old, ~10,000 new cases ... transformation to acute ... #hematology #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Algorithm Hodgkin Lymphoma ... Responsive to Treatment ... Treated Like Acute ... growth, response to treatment ... pathophysiology #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... Kawasaki, Nephrotic syndrome
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... neutrophil count < 500 cells ... : Tumor Lysis Syndrome ... Hyperuricemia • Acute
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... (90-95% of cases ... Treatment • Early ... classification #hematology ... #oncology #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... or acute leukemia ... diagnosis #workup #oncology ... #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... Marginal Zone Lymphoma ... Marginal zone lymphoma ... Paraproteinemias #Hematology ... #Diagnosis #Oncology