35 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... and Treatment of ... #TumorLysis #Syndrome ... #management #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... like Burkitt's lymphoma ... in high grade lymphoma ... #Syndrome #TLS ... #oncology #management
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... of Clinical TLS ... MatthewHoMD #TLS ... #management #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... leukapheresis - TLS ... cells releasing ... #Syndrome #TLS ... diagnosis #management #hematology
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... Burkitt, SCLC Cells ... #Syndrome #TLS ... Pathophysiology #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... neutrophil count < 500 cells ... EMERGENCIES: Tumor Lysis ... #differential #
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
change disease • Hematologic ... malignancies Treatment ... Interleukin-2) • Tumor lysis ... #AKI #Cancer #Oncology ... #Differential #
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Non-Hodgkin's Lymphoma ... Reed-Sternberg Cells ... • Hodgkin's Lymphoma ... Algorithm #Causes #Hematology ... #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involvement Differential ... • Other hematologic ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... Responsive to Treatment ... growth, response to treatment ... pathophysiology #Hematology ... Diagnosis #NonHodgkin #differential