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diagnosis management atopic leukemia mds medications myelodysplastic topical anemia aplastic apml chronic cll differentiation leukostasis lymphocytic myelodysplasia sweet syndromes tumor
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... leukapheresis - TLS ... cells releasing ... #Syndrome #TLS ... diagnosis #management #hematology
Atopic Dermatitis - Topical Treatment Options First Line: Topical Corticosteroids - High Potency: Betamethasone
Atopic Dermatitis ... - Topical Treatment ... After non-pharmacologic ... #Medications #Pharmacology ... #Dermatology #Management
Atopic Dermatitis - Topical Treatment Options First Line: Topical Corticosteroids - High Potency: Betamethasone
- Topical Treatment ... therapy is non-pharmacologic ... patients using TCS ... #Topical #Treatment ... #Dermatology #Management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... febrile neutrophilic dermatosis ... diagnosis #management #hematology ... #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... , breast CA - Hematologic ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... & DIC • Tumor lysis ... syndrome: Develops ... #Leukemia #Hematology ... #Oncology #Diagnosis
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