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Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... hyperparathyroidism, Malignancy ... Pseudohyperparathyroidism, Renal ... #Causes #differential ... calcium #high #endocrinology
Causes of Hypercalcemia - Differential Diagnosis Algorithm • Primary Hyperparathyroidism • Possible Familial Hypocalciuric Hypercalcemia
Causes of Hypercalcemia ... Differential Diagnosis Algorithm ... of Malignancy ... Differential #Diagnosis #Algorithm ... #Causes #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Differential Diagnosis Algorithm ... /lsotretinoin Malignancy ... Immobilization • Adrenal ... Differential #Diagnosis #Algorithm ... #Endocrinology
Treatment algorithm for malignancy-associated hypercalcemia. Hypercalcemia - Renal Failure → Dialysis with low Ca++ bath Aggressive IV hydration
for malignancy-associated ... Renal Failure → ... Calcitonin Refractory Cases ... #associated #hypercalcemia ... #management #endocrinology
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... disease of bone Malignancy ... , adrenal, prostate ... #Causes #endocrinology
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Lithium-associated ... thyrotoxicosis, adrenal ... #Causes #Differential ... #Diagnosis #Endocrinology
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 Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - ... Differential Diagnosis Algorithm ... Tumors: Lung, SCC, renal ... Differential #Diagnosis #Algorithm ... #causes #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Causes of Adrenal ... Differential Diagnosis Algorithm ... Infiltrative: Malignancy ... Differential #Diagnosis #Algorithm ... #Causes #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... Weakness, fatigue, nausea ... hyponatremia, hyperkalemia ... Differential #Diagnosis #Algorithm ... #endocrinology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Insufficiency • Adrenal ... Liver Failure • Hypercalcemia ... • Anemia • Malignancy ... #causes
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