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diagnosis differential management dermatology syndrome eosinophilia classification clinical rheumatology anemia dress drugreaction photo skinrash table ucsdh algorithm basophils comparison hemolysis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Types: • Leukocyte ... - Allergic ... proteins on plts, leukocytes ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... • Allergic reaction ... proteins on plts, leukocytes ... Causes purpura & ... diagnosis #management #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
blood is a liquid ... Blood saves lives ... unnecessary and cause ... Transfusions are ... #Thresholds #Hematology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... Examples: Acute transfusion ... recruitment of leucocytes ... #types #allergy
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... of high parity blood ... without other cause ... #Reactions #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... released during an allergic ... reaction or asthma ... Or Inflammatory Reactions ... #hematology #basophils
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... are asthma, allergy ... , drug reaction, ... Differential #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic Causes ... Intravascular Causes ... prosthetic valve • Transfusion ... reactions ex. ... classification #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... reaction, Paroxysmal ... reaction • Intrinsic ... Extravascular #Causes ... differential #diagnosis #hematology
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