38 results
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Types: • Leukocyte ... proteins on plts, leukocytes ... High mortality. ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... the banked donor blood ... proteins on plts, leukocytes ... High mortality. ... #diagnosis #management
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Reactions TRALI ... Critical illness, high ... , female of high ... parity blood donor ... #Reactions #hematology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... Crush injury • Blood ... reaction - Tumor ... Blood transfusion
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... Crush injury • Blood ... reaction - Tumor ... Blood transfusion
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
Leukocytosis: The term 'leukocyte ... in peripheral blood ... Leukemoid reaction ... part automated differential ... precursor cells to leukocytes
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Cold AIHA, Transfusion ... reactions, Drug-associated ... - Peripheral Blood ... #Hemolysis #Differential
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Hypertriglyceridemia • Uremia High ... Content • RBC Transfusions ... turnover • Acute blood ... Effect • RBC Transfusions ... Diagnosis #DM2 #Differential
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Potassium-rich diet • Blood ... transfusion • ... Normal, Renin High ... hypoplasia Aldosterone high ... nephrology #potassium #differential
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
HyperKalemia - Differential ... glycosides • High ... dietary intake • Blood ... transfusion • ... #HyperKalemia #Differential