30 results
hematology management differential oncology causes acute chronic deficiency dermatology disease leukemia mds myelodysplastic thrombocytopenia thrombocytosis activation agglutinin aplastic arteritis b12
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... cell transplant is ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelofibrosis Infectious ... Inflammatory: • IBD ... effect following treatment ... Iron deficiency anemia ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Idiopathic • Infections ... of CD34+ cells is ... Treatment: ... #oncology #hematology ... #diagnosis #management
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... Algorithm Labs ... Gastrectomy, WHDA syndrome ... Tropical sprue, IBD ... #hematology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
RNA level ↑ • Leukocyte-lymphocyte ... enzymes ↑ • Mild anemia ... Viral hepatitis Diagnosis ... antibody test) Treatment ... #HIV #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... Differential Diagnosis ... of a serious infection ... of infection relative ... neutrophil #WBC #CBC #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Algorithm Endocrine ... Hematologic • Anemia ... • Malignancy Infectious ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
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