32 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal Involvement ... Lupusreference #Renal ... #diseases #SLE ... classification #types #rheumatology
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Urinalysis & Urine ... exclusively on urine ... • Ketones • Leukocyte ... used with normal renal ... dipstick #nitrite #leucocyte-esterase
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... cells - Normal • Renal ... also be seen if urine ... glomerular disease • Leukocytes ... contamination #Urine
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Blasts > 10% leukocytes ... Splenomegaly • ↑ Leukocyte ... AML Dx: • ↑ Leukocyte ... differentiated leukocytes ... #Leukemia #Hematology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Arthritis R Renal ... #IMDAMNSHARP #sle ... erythematosus #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE ... Summary #diagnosis #rheumatology
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
Hematuria in Post-Renal ... infections (HPV, EBV), Renal ... Goodpasture's syndrome, SLE ... #Hematuria #Renal ... kidney #blood #urine
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... Special cases (e.g. renal ... #Measurement #SLE ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Abdominal pain (20%) Renal ... Thrombocytopenia #Lupus #SLE ... symptoms #diagnosis #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... - SEROSITIS - RENAL ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus