83 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Primary Biliary Cirrhosis ... pathophysiology #pbc ... #psc #hepatology ... #comparison
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... - Differential Diagnosis ... #Normocytic #Anemia ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential Diagnosis ... • Extrinsic RBC ... • Intrinsic RBC ... #Differential #Diagnosis ... #Algorithm #hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Autoimmune Hemolytic Anemia ... Spherocytes • Treatment ... transient hemolysis • Treatment ... #hematology #diagnosis ... #comparison
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... hepatomegaly • Labs: anemia ... platelets, persistent WBC ... #Algorithm #hematology ... #WBC #Leukemoid
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... RBC are produced ... destruction of RBC ... 150,000 per mcL, and leukocytes ... majority of the leukocytes
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Chronic disease anemia ... Sideroblastic anemia ... #differential #diagnosis ... #hematology #microscopy
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... Differential Diagnosis ... counts may delay diagnosis ... #differential #diagnosis ... #CBC #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... - Differential Diagnosis ... • Anemia of Chronic ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Common RBC Inclusions and Associations
 • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia
 • Heinz
Common RBC Inclusions ... Severe hemolytic anemia ... , Hemolytic anemia ... Inclusions #Bodies #diagnosis ... #hematology