13 results
diagnosis differential hemolytic management oncology hemolysis algorithm causes chronic cll extravascular intravascular leukemia lymphocytic aiha antibody bandemia cbc cell classification
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Warm Autoimmune ... Spherocytes • Treatment ... #hematology #diagnosis ... #comparison
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... ↑ LDH • Anti-RBC ... Pouchelon #Warm ... diagnosis #management #treatment ... #rheumatology
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... Warm AIHA: 1) Steroids ... Cold AIHA: • Warm ... #management #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Membrane): - Autoimmune ... : Warm AIHA, Cold ... Defects: Sickle cell anemia ... Differential #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... (AIHA) "Warm" ( ... • Intrinsic RBC ... differential #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Immune-Mediated • Warm ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... immune-complex hemolytic anemia ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup ... #hematology #testing
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... Corticosteroid use • Autoimmune ... Even with normal WBC ... relative to both WBC ... #CBC #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... transformation) Treatment ... marrow failure with anemia ... Leukemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... Hypogammaglobulinemia • Warm ... Leukemia #diagnosis #workup ... #oncology #hematology
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