29 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... : Fever (50%), Depression ... Cranial nerve lesions ... Abdominal pain ... symptoms #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
• Rheumatic fever ... Discoid skin lesions ... • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... lupus. ... CTILD #Diagnosis #Differential ... #Comparison #Table ... #Pulmonary #Rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... (aPL) 30-45% Differential ... Lupusreference #SLE #Systemic ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... is the main clinical ... lupus erythematosus ... Diagnosis #Management #Hematology ... #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... lupus erythematosus ... , Drug-induced Lupus ... ANA #patterns #rheumatology ... #diagnosis #differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
and fingers, or pain ... the face (many differential ... 9) Unexplained fever ... diagnosis #sle #clues #system ... erythematosus #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... malaise) - Muscle pain ... Inflammation and pain ... , breast CA - Hematologic ... ’s syndrome - Lupus
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... proximal joints, Fever ... Diffuse muscle pain ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... papulosquamous lesions ... permanent alopecia Differential ... Arthritis: • Joint pain ... #Diagnosis #Rheumatology