48 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... Supportive with treatment ... hepatomegaly and anemia ... cholestasis: • Fever ... #differential #diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Treatment: • Consider ... if neutropenic fever ... progress to MDS or acute ... #treatment #hematology
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... schistosomiasis • Pyemia ... Non-Infectious Causes ... Brucellosis Faget's Sign ... #Differential #Diagnosis
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... kidney disease, Acute ... : Alcohol use, Liver ... Myelodysplastic syndrome ... #causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... and petechiae Causes ... Treatment: ... #diagnosis #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... Inflammation: high fever ... TREATMENT: ​• Acute ... gabrieltalledop #Oroya #Fever
Signs and Symptoms Associated With Different Headache Etiologies
 • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... , anemia, febrile ... coital headache • Fever ... #headache #signs ... #differential #diagnosis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... and hepatorenal syndrome ... • Budd Chiari syndrome ... • Cirrhosis/acute ... #causes #hepatology