22 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Pain Rash ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... #joint #pain #skin ... #rashes #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... fever • Mononeuritis ... • New murmur, fever ... #pain #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... ) General: Fever ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... lesions Abdominal pain
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... the face (many differential ... 9) Unexplained fever ... including in children (pediatric
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
muscle weakness, rash ... Rheumatica • Pain ... , Fever, No muscle ... Diffuse muscle pain ... Myopathies #myopathy #differential
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... acute rheumatic fever ... Chronic = RA, SLE ... #Joint #Pain #MSK ... approach #workup #differential
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever ... , breast CA - Hematologic
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... • Rheumatic fever ... streptococci (rheumatic fever ... arthritis • SLE ... #pain #Differential
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint ... pain/Night sweats ... arthritis - SLE ... Acute rheumatic fever
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Arthritis: • Joint ... pain • Swan neck ... to: Arthritis, Fever