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diagnosis causes algorithm rheumatology management dermatology classification comparison pulmonary cardiology hepatology infectiousdiseases oncology systemic treatment joint pain rash arthritis msk
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... inclusions - If infection ... bartonella (oroya fever ... #Anemia #Differential ... #hematology #testing
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
of Chronic Disease ... • Bleeding • Hemolysis ... of Chronic Disease ... Renal Disease, Liver ... , Chronic Infection
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... , Liver disease, ... liver disease, ... RBC #Morphology #differential ... #diagnosis #hematology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... and bacterial infections ... schistosomiasis • Pyemia ... with profound hemolysis ... #Patterns #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... spherocytosis) • Infections ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... malignancy, autoimmune disease ... Recent travel/Fevers ... , DAT (-) → Infection ... #Anemia #Differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Macroangiopathic, Infections ... Non-megaloblastic: Liver ... disease, Alcoholism ... #Diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
kidney disease, ... (e.g. cancer, infection ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
Causes of Fever ... Other: • Drug fever ... • Factitious fever ... • Rheumatic fever ... UnknownOrigin #FUO #Chronic
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypothyroid • Liver ... Disease • Alcohol ... #differential # ... diagnosis #algorithm #hematology ... #workup
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