34 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... Supportive with treatment ... hepatomegaly and anemia ... cholestasis: • Fever ... hepatology #hepatitis #differential
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Treatment: • Consider ... if neutropenic fever ... diagnosis #management #treatment ... #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... • Rheumatic fever ... Sarcoidosis #dermatology ... #rashes #differential ... #diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH) Clinical ... Features: Fever ... : ↑↑ ferritin, Anemia ... 8 criteria: • Fever ... Lymphohistiocytosis #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... mountain spotted fever ... #Diagnosis #hematology ... #rheumatology #
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... bartonella (oroya fever ... #Differential # ... Algorithm #workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... : • Fever • Fatigue ... index < 2 • EPO Level ... Treatment: ... #oncology #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... is the main clinical ... - Nonremitting fever ... Diagnosis #Management #Hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... (SLE) General: Fever ... lesions Abdominal pain ... ) Blood (75%): Anemia ... symptoms #diagnosis #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... explain symptoms • Fever ... : 33% • Treatment ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology