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diagnosis disease hematology infectiousdiseases syndrome microbiology oncology sle causes erythematosus systemic arthritis chagas signs symptoms trypanosomiasis american checklist chronic classification
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... life-threatening • Treatment ... #Summary #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Erythematosus Clinical ... Constitutional domain: Fever ... least 2 joints • Neurologic ... Erythematosus #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management ... #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... comparison #table #rheumatology
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
Diagnosis and Management ... Summary Clinical ... active ROM +/- fever ... viral arthritis Workup ... #Summary
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Summary Kawasaki ... Presentation: • Fever ... Diagnostic Criteria - Fever ... KD #vasculitis #rheumatology ... #treatment
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... fraction < 20% Differential ... Disease #diagnosis #management ... #treatment #rheumatology
Tularemia - Diagnosis and Management Summary Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection •
Diagnosis and Management ... Summary Francisella ... Ulceroglandular: Fever ... Culture & GS, PCR Treatment ... #treatment #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
: fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
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