25 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... and petechiae Causes ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Systolic Murmurs - Differential Diagnosis Algorithm
Benign / Flow / Hyperdynamic:
 • Pregnancy
 • Fever
 • Anemia
Supravalvular
Pregnancy • Fever ... • Rheumatic Fever ... • Rheumatic Fever ... • Rheumatic Fever ... #causes
Tachypnea - Differential Diagnosis Framework

Definitions
 • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults
 •
Tachypnea - Differential ... deep breathing Pulmonary ... effusion/Tamponade Hematologic ... • Temperature/FEVER ... Tachypnea #Hyperpnea #Differential
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... death Neutropenic Fever ... Constipation • Nausea ... #differential #
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... explain symptoms • Fever ... , and CXR with pulmonary ... edema) • Fever ... diagnosis #comparison #table
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... - Differential ... Diagnosis Algorithm ... Neoplastic / Hematologic ... Chronic Obstructive Pulmonary
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... : • 80% have fever ... Lung #Abscess #pulmonary ... #differential # ... causes #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... hepatitis • Pulmonary ... diagnosis #management #treatment ... #rheumatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... Treat underlying cause ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... initiation • Differential ... diagnosis #management #hematology ... #oncology