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diagnosis management hematology pain algorithm causes erythematosus msk oncology sle arthritis classification dermatology gout hodgkins lung lymphoma myopathy myositis syndrome
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
acute rheumatic fever ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup ... #differential #
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
, Fever, No muscle ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Pain - Differential ... Genitourinary Infection ... • Rheumatic Fever ... Arthritis • Systemic Lupus ... • Rheumatic Fever
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... • Rheumatic fever ... lesions • Discoid lupus ... #skin #rashes #differential ... #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... SLE, Rheumatic fever ... • New murmur, fever ... #pain #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Malar rash 40% - Fever ... (aPL) 30-45% Differential ... Other auto-immune, Infectious ... symptoms #mimickers #differential ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... - Autoimmune Rheumatologic ... • Rheumatic fever ... streptococci (rheumatic fever ... #pain #Differential
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... the face (many differential ... 9) Unexplained fever ... , when infection ... erythematosus #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... symptomatology Differential ... Complex: Systemic lupus ... allopurinol), Infection ... DAH, rule out infection
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
initiation of smoking; Fever ... brown sputum, fever ... Travel hx, food hx; Fever ... #differential # ... diagnosis #comparison
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