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management comparison anemia aplastic chronic cll dermatology differential hemeonc hodgkins lymphocytic lymphoma syndrome apml classification compared differentiation emergencies erythemas nonhodgkins
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Symptomatic anemia Diagnosis ... if neutropenic fever ... to MDS or acute leukemia ... #management #treatment ... #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever ... #dermatology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... minimal tumor burden Diagnosis ... ) B symptoms → fevers ... #oncology #hematology ... #hemeonc #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... phenomenon CLL Diagnosis ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Pel-Ebstein fever ... involved) • No leukemic ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
explain symptoms • Fever ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... syndrome): - Hematologic ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Renal Failure Treatment ... #management #hematology ... #oncology
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