82 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... Supportive with treatment ... cholestasis: • Fever ... Hepatobiliary #hepatology ... #hepatitis #differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... - Pel-Ebstein fever ... Noncontiguous spread • Clinical ... involvement Differential ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... : Fever, Arthralgia ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Script Signs and symptoms ... megaloblastic anemia Treatment ... if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... disease, liver ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Croup Diagnosis and Management Pearls
Common childhood illness, usually viral and self limiting. Characterised by a seal-like
Diagnosis and Management ... hoarse voice +/- fever ... rhinorrhea, and fever ... Treatment: Single ... #pediatrics #peds
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... of liver disease ... Idiosyncratic #differential ... gastroenterology #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... the chest/trunk Symptoms ... Daily high spiking fever ... - Fever spikes ... Fever of at least
Pneumocystis jirovecii Pneumonia 
Clinical 
 • Caused by Pneumocystis jirovecii (formerly carinil) 
 • Immunocompromised host
jirovecii Pneumonia Clinical ... CD4 < 200 • Symptoms ... 2—3 weeks • Fever ... often elevated Treatment ... Pneumonia #Diagnosis #Management