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diagnosis differential treatment disease hematology sle syndrome vasculitis erythematosus systemic arthritis dermatology giantcell oncology classification comparison headache joint msk myositis
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... /Symptoms Alopecia ... , Fever, Malar rash ... , Arthralgia / arthritis ... #rheumatology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... GCA is almost never ... yrs old; F>M Signs ... /Symptoms: - Fever ... #Symptoms #Vasculitis
Temporal (Giant cell) Arteritis Risk Factors: • Age (almost never occurs before age 50) Clinical: •
Temporal (Giant cell) Arteritis ... • Age (almost never ... Constitutional symptoms ... Temporal #GiantCell #Arteritis ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Malar rash 40% - Fever ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Suggestive of: Lupus ... Suggestive of: Lupus ... not be seen try focus ... Suggestive of: Rheum Fever ... migrans: • Target sign
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
Constitutional: Fever ... Subcutaneous nodules, lupus ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Constitutional domain: Fever ... Acute cutaneous lupus ... • Arthritis domain ... Erythematosus #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
• Rheumatic fever ... • Gonococcal arthritis ... • Psoriatic arthritis ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
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