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diagnosis management hematology oncology antibiotics hemeonc hemophagocytic hlh infant lp lymphohistiocytosis pediatrics peds stepbystep stratification sweet acute apml criteria dermatosis
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
or absence of fever ... If fever is present ... but without a fever ... #Diagnosis #Dermatology ... #Nikolsky #Febrile
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... components of the algorithm ... an infant with fever ... Pediatrics #Peds #Febrile ... Stratification #Fever
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... : - If febrile ... Low calcium • Treatment ... diagnosis #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Attempt if high risk ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... acute or subacute febrile ... following: • Fever ... • Bicytopenia Treatment ... #hematology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... to identify low-risk ... empiric antibiotic treatment ... #Antibiotics #Risk ... Stratification #Fever
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Criteria for Sweet Syndrome ... (Acute Febrile ... Fever, temperature ... Excellent response to treatment ... #Dermatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... work-up - If febrile ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
consideration in febrile ... Characteristics: Persistent fever ... Persistent high fever ... Fever b. ... Diagnosis #Management #Hematology
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