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diagnosis management hematology differential oncology syndrome hemeonc pericardial activation apml biopsy cardiogenic causes checklist chf differentiation emergencies endocarditis heartfailure hemopericardium
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
of Pericardial Effusion ... Non-Infectious: • Rheumatologic ... Mediterranean Fever ... #Pericardial #Effusion ... Diagnosis #Causes #cardiology
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework IATROGENIC DISEASE Secondary to invasive cardiac procedures NONIATROGENIC • Malignancy (e.g., metastatic spread:
Hemorrhagic Pericardial Effusions ... • Malignancy (e.g ... Mediterranean fever ... #Pericardial #Effusion ... Differential #Diagnosis #cardiology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Diagnosis #Management #Hematology ... #Rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... - Pel-Ebstein fever ... the spleen or liver ... #NonHodgkins #comparison ... #differential #hematology
Myocarditis 5 Principles of Myocarditis: 1. Build clinical suspicion 2. Decide on EMBx 3. Manage acute cardiac injury 4. Manage chronic
Presentation: - Fever ... Pericarditis, Tamponade EKG ... Low voltage Treatment ... diagnosis #management #cardiology
Severe Heart Failure & Cardiogenic Shock - Management Checklist Evaluation - EKG & echocardiography
Evaluation - EKG ... and/or digoxin level ... edema - Large effusion ... Revascularization, treatment ... #HeartFailure #Cardiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Prednisone 5mg/kg ... Subacute-Acute: • Common: fever ... HoTN, edema and effusions ... diagnosis #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... unless worrisome EKG ... diagnosis #management #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... interventional radiology ... or HSCT - CRS: fever ... therapy - Symptoms: fever
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