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diagnosis cardiology management erythematosus hematology systemic signs symptoms syndrome activation apml autoantibodies causes classification clinical conditions differentiation echocardiogram effusion extrarticular
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: ... Fever (50%), Depression ... effusion, Restrictive lung ... Pericarditis, Endocarditis ... symptoms #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... , Rheumatic fever ... • New murmur, fever ... , Rheumatic fever
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Malar rash 40% - Fever ... Myositis 4% - Lung ... involvement 3% SLE-Related ... Lupusreference #SLE ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... permanent alopecia Differential ... • Libman-Sacks endocarditis ... to: Arthritis, Fever
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Pericardial Effusion - Differential ... Non-Infectious: • Rheumatologic ... : SLE, Rheumatoid ... Mediterranean Fever ... - Metastatic: Lung
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... erythematosus [SLE ... #Rheumatology
Tricuspid Valve Endocarditis on POCUS Echocardiogram Patient with active IVDU presents with fever, sepsis. More likely
Tricuspid Valve Endocarditis ... presents with fever ... frequently have lung ... CT cor image ... Echocardiogram #clinical #cardiology
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 Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... initiation • Differential ... #oncology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... • Autoimmune (SLE ... night sweats, fever ... Marantic (NTBE) Differential ... Persistent bacteremia/fevers
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential ... , verrucous) - Lung ... • Autoimmune (SLE ... night sweats, fever ... hematuria, + RF Treatment
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