18 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... : High spiking fever ... : high fever, CRP ... #AdultOnset #Stills ... #rheumatology #diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... #disease #AOSD
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... #AdultOnset #Stills ... diagnosis #management #treatment ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... #Rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... pulmonary edema) • Fever ... : No • Treatment ... diagnosis #comparison #table
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
confusion and fever ... This is relapsing fever ... P. h. humanus sticks ... Fever recurs over ... The table below
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... +, Adult-onset Still ... Unknown cause Treatment ... #summary #rheumatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
: • 80% have fever ... 38 degrees • Chills ... decubitus - air fluid level ... Intervention: - Fevers ... shows a small, stable
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Insect stings Disease ... symptoms - Headache, fever ... Urticaria #diagnosis #rheumatology ... #comparison #table
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Renal Failure Treatment ... diagnosis #management #hematology ... #oncology