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Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
• Rickettsial diseases ... • Behcet's syndrome ... • Hyper-IgD syndrome ... receptor-associated periodic syndrome ... Brucellosis • Liver
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
amebic abscess of liver ... or elevation of liver ... Typhoid, amebic liver ... fluke, amebic liver ... ancylostomiasis, liver
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver ... Disease (Cirrhosis ... • Hepatorenal Syndrom ... (HRS) • Liver ... SBP) #ESLD #Liver
Liver Abscess on POCUS Ultrasound

Fever and RUQ pain/tenderness isn't always chole. In this patient population make
Liver Abscess on ... POCUS Ultrasound ... Fever and RUQ ... sure to sweep the liver ... with spontaneous liver
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... hepatic crisis: • Fever ... cholestasis: • Fever ... progressing to acute liver ... Liver transplant
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... Lemierre's syndrome ... Brucellosis, Q fever ... Mediterranean fever ... , Factitious fever
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... Liver disease ... - Acute fatty liver ... - Nephrotic syndrome ... Mediterranean fever
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... duplex or CTA • Liver ... Liver biopsy • ... udaygulati #FUO #Fever
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... thrombocytopenia • Liver
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... SLE, Rheumatic fever ... stenosis - Rheumatic fever ... • New murmur, fever