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diagnosis hematology differential management monoclonal mgus aflp causes hellp hodgkins leukemia lymphoma mds myelodysplastic obstetrics pregnancy significance table thrombocytopenia ttphus
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... capillary leak syndrome ... • Schnitzler syndrome ... Differential #Diagnosis #hematology ... #oncology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... Myelodysplastic syndrome ... - Thalassemia, Liver ... Hemolytic uremic syndrome ... #differential #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Presentation: • Fever ... Constitutional Syndromes ... index < 2 • EPO Level ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Pernicious Anemia ... Myelodysplastic Syndromes ... #Macrocytic #Anemia ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... thalassemia • Anemia ... : Alcohol use, Liver ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... and Acute Fatty Liver ... Pregnancy (AFLP) Three syndromes ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... No evidence of anemia ... insufficiency, Anemia ... #Significance #hematology ... #diagnosis #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... with leukopenia, anemia ... Diagnosis #Management #Hematology ... #Rheumatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... Differential #Diagnosis #hematology
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