47 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... Fever (50%), Depression ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... erythematosus [SLE ... #Rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
(SLE) - Typical ... Signs/Symptoms ... Alopecia, Fever, ... #Signs #Symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Pancreatitis - Elevated Liver ... - Budd Chiari Syndrome ... Erythematosus #SLE ... pathophysiology #signs #symptoms
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... fever • Mononeuritis ... stenosis - Rheumatic fever ... • New murmur, fever
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #differential #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... glycoprotein I (ß2GP), Lupus ... LAC) • Sjogren Syndrome ... #associations #table
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... Non-autoimmune rheumatologic ... : • Symptoms limited ... to: Arthritis, Fever
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... , neonatal lupus ... overlap syndromes ... erythematosus #diagnosis #rheumatology ... #table #ANA