33 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
DILI and Type of Liver ... Injury #Medications ... #LiverInjury #Hepatology ... #Pharmacology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... • Rheumatic fever ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... death Neutropenic Fever ... New-onset back pain ... Chest and shoulder pain ... Dyspnea, chest pain
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
30mm length) • Fever ... • Abdominal pain ... Diagnosis #criteria #hematology ... #oncology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid - Indications ... and Pharmacology ... diarrhea & abdominal pain ... #Pharmacology # ... hematology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... proximal joints, Fever ... Anti-retrovirals, Gemcitabine Lupus ... Diffuse muscle pain ... uncommon 5-15% of lupus
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... is the main clinical ... SJIA], systemic lupus ... Diagnosis #Management #Hematology ... #Rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: Fever ... lesions Abdominal pain ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
After non-pharmacologic ... has a different level ... is the newest medication ... #Pharmacology # ... Dermatology #Management