21 results
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... #Kidney #Injury ... #AKI #Cancer #Oncology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Pigment, Protein) • AIN ... #Acute #Kidney ... #Injury #Differential
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Acute Kidney Injury ... , tenofovir • AIN ... #Acute #Kidney ... #Injury #Medications ... #Drugs #pharmacology
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... cardiorenal syndrome) • Liver ... nephritis (AIN) ... tract infection • Medications ... #Acute #Kidney
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... (AKI) - Management ... • AIN → Consider ... #Acute #Kidney ... #Injury #treatment
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Kidney Injury ... kidney injury is ... • Treatment includes ... #Vancomycin #AKI ... #pharmacology #
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Circulation Failure Kidney ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Indications for ... ascites removed • Acute ... kidney injury ( ... Management #Cirrhosis #treatment ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... duration), Several medications ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Algorithm #hepatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
symptoms: - Muscle pain ... - Abdominal pain ... declines > ALT) • AKI ... + myoglobin AKI ... nephrotoxicity to kidney