7 results
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
: Mechanism of Action ... in Hepatic Encephalopathy ... #Lactulose #pharmacology ... mechanism #ammonia #hepatology ... #pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... → ↓ Hepatic Bile ... Acid Pool → ↑ Hepatic ... sequestration #pathophysiology ... #pharmacology #
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... Indications and Pharmacology ... small amount of hepatic ... • Duration of Action ... #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... transfusion • Pathophysiology ... #hematology #diagnosis ... #comparison #table
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... adrenergic #receptors #actions ... #pharmacology # ... pathophysiology ... #comparison #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Bumetanide, Ethacrynic acid ... heart failure, liver ... the Nonspecific Cation ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... formation of new uric acid ... irritation, rash, fever ... Slow onset of action ... #pathophysiology