46 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... ALT ↑ bilirubin level ... #Diagnosis #Management ... #Hematology #Rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
- Generalized Differential ... disease Creatinine ... Myelodisplastic syndrome ... Psychiatric Disease ... #generalized #dermatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Diseases Nail ... discoloration) • Liver ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
, the differential ... includes Kawasaki disease ... and toxic shock syndrome ... #Diagnosis #Dermatology ... #Differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... solid cancers • Systemic ... #diagnosis #management ... #treatment #rheumatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... and hepatorenal syndrome ... • Budd Chiari syndrome ... • Infiltrative diseases ... Veno-occlusive disease
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Neurologic system ... Genitourinary system ... Cardiovascular system ... #joint #pain #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... disease. ... Musculoskeletal system ... Episcleritis Signs ... , breast CA - Hematologic