33 results
diagnosis disease oncology hemophagocytic hlh lymphohistiocytosis symptoms algorithm anemia aplastic causes dermatology differential erythematosus lupus sle systemic workup activation adultonset
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Clinically ... suspect underlying hematologic ... Diagnosis and Treatment ... #HES #Hematology ... eosinophils #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
syndromes Clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... megaloblastic anemia Treatment ... if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Diagnosis: HLH signs ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: Fever ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Susac Syndrome - Clinical Triad - Central nervous system dysfunction - Branch retinal artery occlusion -
Susac Syndrome - ... Clinical Triad ... arterioles - Treatment ... Triad #Diagnosis #Management ... #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... Disease #diagnosis #management ... #treatment #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
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