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diagnosis management hematology table aflp differential hellp obstetrics pregnancy thrombocytopenia ttphus anemia aplastic effusion endocarditis fever hantavirus hyperthermia leukostasis lysis
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... child * Severe cases ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
production • Treatment ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... • Treatment: ... #Hyperthermia #comparison
Hantavirus Pathogen: Hantavirus - Rodents are the primary reservoir Transmission: • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... • Prodrome: fever ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology #infectiousdiseases
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Causes of Pericardial ... Non-Infectious: • Rheumatologic ... Mediterranean Fever ... Differential #Diagnosis #Causes ... #cardiology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... Hemolysis, Elevated Liver ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... and petechiae Causes ... index < 2 • EPO Level ... aplastic anemia Treatment ... Anemia #oncology #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... vasculitis: 10%-16% Liver ... Adenocarcinoma Treatment ... #Rheumatology #
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Cholesterol emboli syndrome ... Septic emboli cause ... hematuria, + RF Treatment ... Differential #Diagnosis #cardiology ... #infectiousdiseases
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